Biology of Aging - University of California, Davis - Instructor: Roger B. McDonald

Class meets
Tues., Thurs. 12:10-1:30
194 YOUNG
CRN# 64982

Instructor
Roger McDonald
3145 Meyer Hall /219-5941
rbmcdonald@ucdavis.edu
TA: Rachael Constant

3426 Meyer Hall /752-6495 rconstant@ucdavis.edu

Course Synopsis

The objective of the course is to familiarize the student with 1) basic concepts in the biological basis of aging, 2) interventions that may modify the rate of aging and 3) an understanding of the biological continuum from fertilization to death. The course is designed for students with limited background in biology. The basic biology requirement needed for entry into the University of California will be sufficient to comprehend the material presented in the course. Topics will include evolution and the genes that determine our life span, the finite life of the cell and its effect on the organism's rate of aging, how the rate of aging in plants, insects, fish, and birds provide insight into human senescence, how fetal development affects the physiology of aging, disease and aging, and interventions that modify the rate of aging and delay death.

A unique aspect of this course is that the entire lecture material will be accessible through an interactive web page. The student enrolled in this course will be able to access the lecture outlines, slides and illustrations used in class (linked to the lecture outline), a glossary of terms, biographical descriptions of important individual contributing to the field of aging research, a list of additional reading and links to other Web sites pertinent to the course, and a course information page. All students are required to obtain an e-mail account.

Important Dates

Thurs, Sept 25 First Day of Instruction
Thurs, Oct. 23 Exam Review
Tues, Oct. 28 Midterm One
Tues, Nov. 11 Veterans Day Holiday (no Class)
Thurs, Nov 27 Thanksgiving Holiday
Tues, Dec 2 Exam Review
Thurs, Dec 4 Midterm Two
Friday, Dec 12

Final Exam 1:30-3:30

Grading

Grades will be based on total points from 3 exam: two midterms and one final exam. The final exam is comprehensive.

Office Hours

Instructor: Roger McDonald
Tuesdays 2-3, Thursdays 10:30-11:30
3145 Meyer Hall
T.A.: Rachael Constant, TBA

Class Mailing List

All students registered for this course will be automatically added  to a course mailing list.   To send questions or comments to class members and the  instructor, simply send e-mail to: bis15-f03@ucdavis.edu and the e-mail will automatically be sent to all those on the mailing list.  The messages sent to the list are archived on the web enabling students to view past messages throughout the quarter.  Upon course completion or if a student drops the course, the student will automatically be dropped from the mailing list.

Text

The textbook for this course is Biology of Aging: Observations and Principles, 2nd Edition, by Robert Arking. The reading material for this course includes items from the textbook and files linked to the lecture notes. You will be responsible for the material contained in these readings, i.e., there will be test questions. The readings will not be discussed in lecture, except for specific questions and areas in which my lectures provide information that is significantly different from the readings. To help you with the material, a review quiz will be provided with each reading assignment. The review quizzes are linked to the lecture notes. 

Textook Scan (first reading assignment)

 

Lecture Notes

Introduction

Lecture Notes
Slides
Review Quiz
Demographics of the Population
Lecture Notes
Slides
Review Quiz
Measuring Life Span & the Rate of Aging
Lecture Notes
Slides
Review Quiz
Physiological Changes
Lecture Notes
Slides
Review Quiz
Evolutionary Theory of Aging
Lecture Notes
Slides
Review Quiz (Hayflick Reading), Review Quiz (Arking Reading)
Cell Aging
Lecture Notes
Slides
Review Quiz
Theories of Aging
Lecture Notes
Slides
Review Quiz
Free Radical Theory
Lecture Notes
Slides
Caloric Restriction
Lecture Notes , Scientific American Article - "The Quest to Beat Aging"
Slides
Alzheimer's Disease
Lecture Notes
Additional Reading Assignments
Physiological Basis of Aging and Geriatrics, edited by Paola S. Timiras, pages 89-94 and 107-111.
USA Today article:  "Too old? Yeah right.
Scientific American article: "The Quest to Beat Aging"

Related Web Sites

Online Biology Books
Virtual Cell
Cells Alive


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Course designed by: Roger B. McDonald, Ph.D.
Department of Nutrition, University of California, Davis
3145 Meyer Hall Davis, CA 95616-8119
Office Phone: (530) 219-5941 Department Fax: (530) 752-8966
Please send comments and questions to:
rbmcdonald@ucdavis.edu

Copyright © 1997 Roger B. McDonald

Note: Portions of this web site have restricted access.  If you are not enrolled in the course, but would like access to the restricted areas of this web site, please contact Roger McDonald, rbmcdonald@ucdavis.edu